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Laboratory Testing of Medical Devices

Laboratory testing of medical devices that share a similar form with cosmetic products

CoLab is a modern testing laboratory in Kyiv specializing in the testing of cosmetic products and raw materials, medical devices, and cosmetic products for animals.

Some medical devices have a dosage form and method of use similar to cosmetic products (creams, gels, solutions, sprays). The CoLab laboratory carries out laboratory testing of such medical devices, in particular for inclusion in the technical documentation for certification purposes.

Our test reports form the basis for regulatory documentation, safety assessment, and substantiation of a product's claimed properties. We carry out laboratory testing whose results are used to demonstrate the conformity of products with the requirements of the technical regulations of Ukraine, the European Union, the United Kingdom, and other international markets.

Forms of medical devices we test:

Creams Gels Solutions Sprays Emulsions Ointments
Legislation

Regulatory Requirements

In Ukraine, medical devices are regulated by the Technical Regulation on Medical Devices, approved by Resolution of the Cabinet of Ministers of Ukraine No. 753 of 02.10.2013, and are subject to a mandatory conformity assessment procedure before being placed on the market.

As part of the conformity assessment, a technical file must be developed for the medical device, containing:

A full description of the device
Substantiation of its safety and efficacy
The results of the relevant laboratory tests

National Standards

In accordance with clause 9 of the Technical Regulation, medical devices that meet the requirements of the national standards included in the list are deemed to comply with the requirements of the Technical Regulation. The list includes monographs (pharmacopoeial articles) of the State Pharmacopoeia of Ukraine.

Similarly, for the EU market, monographs of the European Pharmacopoeia (Eur Ph) are used.

Regulatory Documents

  • Resolution of the CMU No. 753 Technical Regulation on Medical Devices (02.10.2013)
  • ДФУ 2.8 State Pharmacopoeia of Ukraine
  • Eur Ph 11.8 European Pharmacopoeia
List of Tests

Organoleptic Parameters

Organoleptic parameters are fundamental characteristics of medical devices that are assessed at all stages of the life cycle. They play a critically important role both in terms of stability and in terms of safety and consumer perception.

Appearance
In-house method of CoLab LLC
Colour
In-house method of CoLab LLC
Odour
In-house method of CoLab LLC
Mass / volume
In-house method of CoLab LLC
List of Tests

Physicochemical Parameters

Hydrogen ion concentration (pH)
ДФУ 2.8, sec. 2.2.3 and/or Eur Ph 11.8, 2.2.3
Viscosity
ДФУ 2.8, sec. 2.2.10 and/or Eur Ph 11.8, 2.2.10
Ethanol content by volume
In-house method of CoLab LLC
List of Tests

Microbiological Parameters

Total aerobic microbial count
ДФУ 2.8, sec. 2.6.12 and/or Eur Ph 11.8, 2.6.12
Mesophilic aerobic bacteria count
ДСТУ ISO 21149:2010 and/or ISO 21149:2017/Amd 1:2022
Detection of Escherichia coli
ДФУ 2.8, sec. 2.6.13 and/or Eur Ph 11.8, 2.6.13
Detection of Pseudomonas aeruginosa
ДФУ 2.8, sec. 2.6.13 and/or Eur Ph 11.8, 2.6.13
Detection of Staphylococcus aureus
ДФУ 2.8, sec. 2.6.13 and/or Eur Ph 11.8, 2.6.13
Detection of Candida albicans
ДФУ 2.8, sec. 2.6.13 and/or Eur Ph 11.8, 2.6.13
Efficacy of antimicrobial preservatives
ДФУ 2.8, sec. 5.1.3 and/or Eur Ph 11.8, 5.1.3
List of Tests

Stability and Compatibility

Determination of the stability of medical devices Including colloidal stability, thermal stability, and stability against microbiological standards
ДСТУ ISO/TR 18811:2019 and in-house method of CoLab LLC
Determination of compatibility with packaging Assessment of the interaction between the device and packaging materials
ДСТУ ISO/TR 18811:2019 and in-house method of CoLab LLC
Determination of PAO (Period After Opening) The period of time after the packaging is opened
ДСТУ ISO/TR 18811:2019 and in-house method of CoLab LLC

Order Medical Device Testing

The CoLab laboratory carries out comprehensive testing of medical devices, the results of which form a scientifically substantiated body of evidence and serve as the basis for the technical documentation (technical file) for the conformity assessment procedure.